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Emergence of West Nile virus lineage 2 in Europe: Characteristics of the first seven cases of West Nile neuroinvasive disease in horses in Austria

dc.contributor.authorNowotny, Norbert
dc.date.accessioned2021-03-01T08:59:24Z
dc.date.available2021-03-01T08:59:24Z
dc.date.issued2019
dc.description.abstractAbstract: We report details of the first seven equine cases of confirmed West Nile neuroinvasive disease in Austria. The cases presented during summer and autumn of 2016 (n = 2), 2017 (n = 3) and 2018 (n = 2). All horses showed gait abnormalities and 6 of 7 horses exhibited fasciculations and/or tremors, and we provide video recordings of these. Three horses also showed cranial nerve involvement. Following rapid improvement, three horses were discharged. Four horses were euthanized due to the severity of clinical signs and subjected to neuropathological examination. West Nile virus (WNV) lineage 2 nucleic acid was detected in 5 of 7 horses, and WNV-specific neutralizing antibodies in all 7 horses. In addition, serologic evidence of WNV infection was found in two out of fourteen in-contact horses. Horses may be considered a sentinel species for human WNV infections, integrating human and veterinary medicine and thus contributing to the one health concept.en_US
dc.identifier.other204-2019.30
dc.identifier.urihttps://repository.mbru.ac.ae/handle/1/184
dc.language.isoenen_US
dc.subjectVirusesen_US
dc.subjectWest Nile neuroinvasive diseaseen_US
dc.titleEmergence of West Nile virus lineage 2 in Europe: Characteristics of the first seven cases of West Nile neuroinvasive disease in horses in Austriaen_US
dc.typeArticleen_US
dspace.entity.typePublication

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